R&D

인진쑥, 마늘 및 오가피 추출물을 포함하는 사료조성물을 이용한 올레인산 강화 닭고기의 제조방법

본 발명은 인진쑥( Artemisia capillaris thunberg. ), 마늘 및 오가피( Acanthopanax ) 추출물을 포함하는 사료조성물을 이용한 올레인산 강화 닭고기의 제조방법 및 올레인산이 강화된 기능성 닭고기에 관한 것이다.

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이솔리퀴리틴을 함유하는 유방암 예방용 식품

본 발명은 이솔리퀴리틴을 함유하는 유방암 예방용 식품에 관한 것으로, 본 발명의 이솔리퀴리틴은 에스트로젠성은 나타내나 안드로젠성은 나타내지 않고, 내분비계 장애물질인 비스페놀-A의 활성을 억제하며, 유방암 세포를 비롯한 암 세포의 증식을 저해하므로, 파이토에스트로젠으로서 호르몬 대체 치료 및 유방암의 예방 및 치료를 위해 사용될 수 있다.

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백화사설초 및 영지버섯 추출물을 포함하는 바이러스 질환의 예방 및 치료용 조성물

본 발명은 항바이러스 활성을 나타내는 백화사설초 및 영지버섯 추출물을 포함하는 조성물에 관한 것으로서, 더욱 상세하게는, PMWS 바이러스, PRRS 바이러스, PED 바이러스, TGE 바이러스, 파보 바이러스 및 디스템퍼 바이러스에 대해 우수한 항바이러스 활성을 나타내는 백화사설초 및 영지버섯 추출물을 유효성분으로 함유하는 약학조성물에 관한 것이다.

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Human adipose-derived stem cells ameliorate repetitive behavior, social deficit and anxiety in a VPA-induced autism mouse model

요약 : Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by impairments in social interaction and communication, and patients often display co-occurring repetitive behaviors. Although the global prevalence of ASD has increased over time, the etiology and treatments for ASD are poorly understood. Recently, some researchers have suggested that stem cells have therapeutic더 보기

HOXC10 as a potential marker for discriminating between amnion- and decidua-derived mesenchymal stem cells.

요약 :
The HOX family of genes plays a fundamental role in the morphogenesis of vertebrate embryonic cells. HOX genes are thought to be important for the regulation of stem cells. We investigated HOX gene expression in
mesenchymal stem cells (MSCs) from human placentas. We isolated MSCs from human placentas and confirmed stemness by fluorescence-activated cell sorting (FACS) analysis and differentiation studies. Using reverse
transcription PCR, mRNA expression of 39 Class I HOX genes was measured in the MSCs. The expression of HOXB6, C4, C8, C10, D3, D4, and D10 were measured by Western blot analysis. HOXC10 was expressed in 10
of 10 amnion-derived MSCs but in only 2 of 10 decidua-derived MSCs. HOXC4 and D10 were expressed in 100% of both amnion-derived MSCs and deciduas-derived MSCs. HOXD4 was silent in all amnion-derived MSCs and deciduas-derived MSCs (n¼10). HOX gene activation patterns might be a useful indicator for the detection of MSCs of different tissue origins. We demonstrated that HOXC10 is a gene that may discriminate between
amnion-derived MSCs and decidua-derived MSCs

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Canine mesenchymal stem cells are effectively labeled with silica nanoparticles and unambiguously visualized in highly autofluorescent tissues.

요약 : 
Background: Development of a method for long-term labeling of cells is critical to elucidate transplanted cell fate and migration as well as the contribution to tissue regeneration. Silica nanoparticles have been recently developed and demonstrated to be biocompatible with a high labeling capacity. Thus, our study was designed to assess the suitability of silica nanoparticles for labeling canine mesenchymal stem cells (MSCs) and the fluorescence afficiency in highly autofluorescent tissue.

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