R&D

- 2015-04-07
Transplantation of Human Adipose Tissue-Derived Mesenchymal Stem Cells Restores the Neurobehavioral Disorders of Rats With Neonatal Hypoxic-Ischemic Encephalopathy
Improving the effects of human adipose tissue-derived mesenchymal stem cells (ASCs) on the demyelination and neurobehavioral function was investigated in an experimental model of neonatal hypoxic-ischemic encephalopathy (HIE). Seven-day-old male rats were subjected to hypoxia-ischemia-lipopolysaccharide and intracerebroventricularly transplanted with human ASCs (4 × 105 cells/rat) once at postnatal day 10 (PND10) or repeatedly at PND10, 17, 27, and 37.
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- 2015-04-07
Transplantation of Human Adipose Tissue-Derived Stem Cells Delays Clinical Onset and Prolongs Life Span in ALS Mouse Model
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that selectively affects motor neurons in the cortex, brain stem, and spinal cord. The precise pathogenic mechanism remains unknown, and there is currently no effective therapy. We evaluated the therapeutic effects of human adipose tissue-derived stem cells (ASCs) in an animal model of ALS. Human abdominal subcutaneous fat tissues were obtained by simple liposuction from donors, and ASCs were isolated from the fat stromal vascular fraction.
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- 2015-04-07
Treatment of progressive supranuclear palsy with autologous adipose tissue-derived mesenchymal stem cells: a case report
INTRODUCTION:Progressive supranuclear palsy is a relentlessly progressive neurodegenerative disorder and is clinically characterized by parkinsonism. Adipose tissue-derived mesenchymal stem cells have recently demonstrated the possibility of treating neurological disorders. Therefore, autologous adipose tissue-derived mesenchymal stem cells transplantation can be an alternative method for treating progressive supranuclear palsy.
CASE PRESENTATION:This study was approved by the Korea Food and Drug Administration through the Emergency Use Investigational New Drug Application. A 71-year-old Asian man from South Korea with progressive supranuclear palsy was treated with five intravenous infusions (each time 2×108 cells) and four intrathecal infusions (each time 5×107 cells) with autologous adipose tissue-derived mesenchymal stem cells expanded under good manufacturing practice conditions.
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- 2016-11-14
감초 추출물 또는 이솔리퀴리틴을 포함하는 파이토에스트로젠 조성물
본 발명은 에스트로젠 활성 및 암 세포에 대한 증식 억제 활성을 나타내는 감초( Glycyrrhiza uralensis Fisch) 추출물 또는 이솔리퀴리틴(isoliquiritin)을 유효성분으로 하는 파이토에스트로젠(phytoestrogen) 조성물에 관한 것으로, 본 발명의 감초 추출물 또는 이솔리퀴리틴은 에스트로젠성은 나타내나 안드로젠성은 나타내지 않고, 내분비계 장애물질인 비스페놀-A의 활성을 억제하며, 유방암 세포를 비롯한 암 세포의 증식을 저해하므로, 파이토에스트로젠으로서 호르몬 대체 치료 및 유방암의 예방 및 치료를 위해 사용될 수 있다.
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- 2016-11-14
고농도의 줄기세포 제조방법
본 발명은 고농도의 줄기세포를 제조하는 방법에 관한 것이다. 본 발명에 따르면, 단기간에 줄기세포를 임상에 적용할 수 있을 정도의 양으로 증식시킬 수 있어, 투여된 줄기세포가 안정적으로 표적 조직에 도달하여 활성을 나타내는 효능을 보다 효율적으로 높일 수 있으므로 줄기세포를 이용한 세포치료 효능을 획기적으로 증진시킬 수 있다.
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- 2017-01-20
내몸을 공격하는 자가면역 질환
내몸을 공격하는 자가면역 질환
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Transplantation of Human Adipose Tissue-Derived Mesenchymal Stem Cells Restores the Neurobehavioral Disorders of Rats With Neonatal Hypoxic-Ischemic Encephalopathy

Transplantation of Human Adipose Tissue-Derived Stem Cells Delays Clinical Onset and Prolongs Life Span in ALS Mouse Model

Treatment of progressive supranuclear palsy with autologous adipose tissue-derived mesenchymal stem cells: a case report

감초 추출물 또는 이솔리퀴리틴을 포함하는 파이토에스트로젠 조성물

고농도의 줄기세포 제조방법

내몸을 공격하는 자가면역 질환

항암면역요법 프로그램

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R&D

Transplantation of Human Adipose Tissue-Derived Mesenchymal Stem Cells Restores the Neurobehavioral Disorders of Rats With Neonatal Hypoxic-Ischemic Encephalopathy

Transplantation of Human Adipose Tissue-Derived Stem Cells Delays Clinical Onset and Prolongs Life Span in ALS Mouse Model

Treatment of progressive supranuclear palsy with autologous adipose tissue-derived mesenchymal stem cells: a case report

감초 추출물 또는 이솔리퀴리틴을 포함하는 파이토에스트로젠 조성물

고농도의 줄기세포 제조방법

내몸을 공격하는 자가면역 질환

항암면역요법 프로그램

Biostar News

Story Cartoon

Contact us

Tag

Family Site

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